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Background: Cosmetic skin lightening (SL) involves topical or systemic agents used to reduce melanin pigmentation for aesthetic purposes. While widely practiced globally, SL remains understudied among Filipino populations in the United States, where culturally specific influences such as historical colorism and digital trends are often overlooked.

Objective: This review examines cultural drivers, commonly used agents, and associated dermatologic risks of SL among Filipino populations.

Methods: This commentary synthesizes relevant literature identified through PubMed and Google Scholar, supplemented by publicly available information and social media trends (e.g., TikTok, Reddit). Search terms included skin lightening, bleaching, hydroquinone, mercury, and Filipino, with inclusion of English-language sources on dermatologic outcomes and cultural drivers published between 2000–2025. Sources were screened for relevance and synthesized thematically across peer-reviewed and public data. Non-dermatologic, non-English, or irrelevant sources were excluded.

Results: Available literature suggests that lighter skin has been associated with higher socioeconomic status and desirability within Filipino communities, now amplified by social media. Evidence is drawn primarily from observational studies, reviews, and regional dermatologic literature, supplemented by online discourse. Common agents include hydroquinone, corticosteroids, mercury-containing products, and glutathione. Use—especially from unregulated sources—poses risks including exogenous ochronosis, post-inflammatory hyperpigmentation, acne, barrier disruption, HPA axis suppression, nephrotoxicity, and neurotoxicity. Filipino populations remain underrepresented and often aggregated within broader “Asian” categories. Findings are derived from limited, heterogeneous sources.

Conclusion: Dermatologists play a key role in mitigating risks through culturally sensitive counseling. Future research should incorporate real-world digital data, including qualitative analysis of online platforms, to better characterize behaviors and inform targeted interventions.

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